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Furthermore, the companion paper demonstrated that the flow balancing valves should be located upstream rather than downstream of the evaporator in order to realize significant benefits.
It is prudent for companies to try to mitigate the potential risks of nanoparticles during the design stage rather than downstream during manufacturing or customer use.
Current strategies for manipulating glycoprotein charge isoform profile involve cell engineering or altering bioprocesss parameters to optimise expression of more acidic or basic isoforms, rather than downstream separation of isoforms.
Anatomical targets for neuroprotection should focus on upstream rather than downstream factors, and could include any part of the retinal ganglion cell, the glia, especially astrocytes or Muller cells, and vasculature.
The premise of the candidate gene approach as a means of identifying causal mechanisms, rather than downstream consequences, is that the functional polymorphism resides either within the candidate gene itself, or is closely linked to it (e.g. cis-regulatory element).
However, it is not known whether NF-Y directly recruits HATs to chromatin, whether NF-Y leads to chromatin remodeling of its target promoters, and whether NF-Y acts upstream rather than downstream of histone tail modifications.
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In this scenario the regional specificity of function is regulated downstream of Hairy1, rather than directly downstream of miR-9.
The majority of diabetics presenting with NSTEMI or cardiogenic shock did not receive a GPI, but in those who did, it was given rather upstream than downstream (Table 2).> Diabetic patients undergoing PCI of left main stem (LM), bypass grafts and more than one segment more frequently received GPI.
Shell makes the vast bulk of its profits on the "upstream" side of the business – producing oil and gas – rather than the "downstream" refining and petrol sales.
Ultimately, this administration must get serious about focusing on improving the health of our population rather than focusing downstream when people are really sick.
In addition, knockdown of ADAM17 had no effect (Figure S1), indicating that ERK phosphorylation is a proximal effect of PMA rather than being downstream of ADAM17-mediated HB-EGF shedding and subsequent EGFR activation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com