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The major oncogenic role of amplified/overexpressed ZNF703 may be dysregulation of differentiation rather than abrogation of cell cycle checkpoints.
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As he got older, he often deflected questions of succession by claiming that he would live forever; this was treated in the press as a rich man's charming eccentricity, rather than an abrogation of responsibility.
The analysis of PPI networks has great potential for aiding our understanding of heritable disease, as the manifestation of a given pathology may result from the perturbation of entire network modules rather than the abrogation of a single gene [ 24].
Noxa deficiency therefore allows investigation of the role of cell death pathways in physiological processes via subtle alteration of cell death sensitivity [ 14], rather than complete abrogation of these pathways such as is the case for Bim or Mcl-1 deficiency.
Although the depletion of SET8 abrogates 53BP1 accumulation at DSBs 11 (Fig 1F and G), this might be an indirect consequence of a global reduction of pre-existing H4K20me upon SET8 depletion (Fig 1B) rather than due to the abrogation of SET8's activity on H4K20 or some other unknown substrate(s) specifically at DSBs.
Thus, the changes induced by MDV infection likely involved subtle variations at specific genomic loci rather than de novo establishment or abrogation of histone marks.> -wrap-foot> Merged peaks are filtered by removing those appearing in only one sample.
American participants in Study 1 rated participation as a significantly more substantial action when agreement was purportedly obtained under opt-in rather than opt-out conditions, and nonagreement as a greater abrogation of responsibility when that decision was made under opt-out rather than under opt-in conditions.
Do productions documenting the abrogation of children's "rights" help improve their lives or do they present the worst rather than the best in families, communities and societies to these same groups and to the wider world?
Potentiation of the anticancer drug BCNU by AMD3100 has also been shown with the intracranially implanted U87 human glioblastoma, though the mechanism for this may have involved abrogation of the survival function of the SDF-1/CXCR4 pathway in the tumour cells (Redjal et al, 2006) rather than prevention of revascularisation after irradiation.
Rather than taking the heat out of the debate on asylum seekers, Labor's bipartisan approach is "turning the screws" on "draconian" policymaking that is a complete abrogation of Australia's responsibilities under the UN refugee convention, Stanhope said.
Shook rather than rolled.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com