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Clearly, it is not discussed herein why discrepant data have been presented but rather mainly where discrepancies come from.
The methods used in the above literature mainly focus on signal denoising, or rather mainly aim at processing signal of the PLM[10] (pulse location managerment).
However, if somatic mutability is truly what has been tuned evolutionarily, then NBDM would be optimized not necessarily over all genes in the genome but rather mainly over those genes that are crucial to somatic performance, perhaps during specific life-history stages or in specific tissues.
However, to the best of our knowledge, these were not based on a rigorous model as the pacemaker rather mainly on the level of the mutation rates.
This problem does not impact the major conclusions of the paper about rod signaling through cones, but rather mainly leads to issues and discussion irrelevant to the main point of the paper.
Unfortunately, in general very little is known about the population and molecular genetics of mongrels (which are, in our case, not cross-breeds of known purebred parents but rather mainly the descendents of mongrels), so our explanation of the present results is based on a most plausible scenario.
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