Sober judgement of events out on the track suggested that the second Epsom trial of the meeting had proved rather less instructive than the first.
The result is hypnotic rather than instructive and, like TV cookery programmes, it's a cinematic experience resembling lap dancing overseen by a duenna.
Fergus's light humor keeps the story amusing rather that instructive (most kids catch on to that kind of hidden lesson pretty quickly), and Mike Lowery's simple, full-page illustrations make the most of the silly action.
The process of scientific change is eliminative and permissive rather than instructive.
Rather than instructive advice, she says, she "would tell a story to illustrate a point".
In vertebrates, Wnt5[5], [6] and Wnt11[7], [8], have been proposed as PCP ligands, but they appear to be permissive rather than instructive since their expression patterns do not coincide with the direction of polarization[4].
Our findings are also of considerable relevance for normal hematopoiesis, as it remains disputed whether key cytokine receptor signaling pathways mediate critical in vivo functions in blood lineage development through purely permissive rather than instructive actions (Enver and Jacobsen, 2009).
Thus, the early function of reelin in the proliferative compartment might underlie its post-proliferative requirement raising the possibility that acts coupling neurogenesis and neuronal migration, perhaps akin to a permissive rather than instructive signal for cellular migration.
We argue that electrical activity might be permissive rather than instructive, with growth at the very early stages of development based on the intrinsic pattern, so accounting for the presence of the superficial patch system in cortical areas that are remote from the potential organizing properties of sensory afferents.
If so, then Notch may be permissive for their expression, rather than instructive, potentially explaining the observation that the regulation of these targets is highly sensitive to synergies with other factors, such as Jak/Stat signalling, and is susceptible to inhibition from Sd or E spl m8.
