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Next, we found by sequence alignments, that the S183I, T260P, I406T and D580E mutations affect amino acids that are rather conserved in all analyzed species, whereas R7C, S144F and F789L affect residues conserved only in higher mammals (Fig. 1B).
The Camellia cp genomes exhibited typical circular structure that was rather conserved in genomic structure and the synteny of gene order.
The proposed G2-G3 domais is rather conserved in angiosperms, whereas G1 and G4 domains and Switches I and II have high frequency of differences between isoforms.
This is not surprising considering that most snoRNAs are involved in rRNA modifications, and that the pattern of rRNA 2'-O-methylation and, likely, pseudouridylation is rather conserved in vertebrates [ 14].
Our findings also indicate that the cagPAI appears to be intact and rather conserved in majority of Iranian strains.
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Here, sites are identified where the residue has not been absolutely conserved in all proteins in the family, but rather conserved within sub-branches of the family.
On the whole, Hox gene inventories of sarcopterygians are rather conserved with only little variations occurring in the anterior or posterior Hox paralogue groups.
Despite the degree of biological organizational level, cells respond to potential DNA damage through a common architecture with a number of rather conserved specific response and repair pathways in an effort to repair the DNA damage to restore homeostasis.
In addition, the nucleotide site 8 is also rather conserved during evolution, suggestive of its potential importance in miRNA-target interactions and/or functions.
Since P is rather conserved along vertebrates, our findings may be of interest in assisted reproduction procedures in humans, animals of economic importance, and endangered species.
Based on our in silico data we did not find binding sites for IRF3 in this region, which is rather well conserved in the analyzed species, with the best conservation between human and cattle in 7 out of 8 human variants, and the worst conservation between chimpanzee and other species (average conservation level 36.57%).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com