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13 14 A bundled intervention that goes beyond measures advocated by the Surgical Care Improvement Project and includes nasal decolonization and glycopeptide prophylaxis could potentially reduce rates of Gram positive surgical site infections, specifically those associated with S aureus.
Our results showed that nasal decolonization was associated with decreased rates of Gram positive surgical site infections and Staphylococcus aureus surgical site infections among patients undergoing cardiac or orthopedic surgical procedures.
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The general trend in chronic dacryocystitis reflects culture-positive rates ranging from 52.5% to 97.3% with isolation rates of gram-positive organisms ranging from 53.7% to 75% and those of gram-negative organisms from 25%to37.4%4% [8 14].
In Brazil the rates of Gram-negative bacteremia in neutropenic patients are high [ 15], rendering quinolone prophylaxis an attractive approach.
Another large study found that resistance rates of Gram-negative bacteria were actually higher in the control population than in the SDD-treated population [ 53].
Diagnostic criteria for infection and the overall rates of Gram-positive, Gram-negative, or fungal infection were similar in the two groups.
No significant between-group differences were found in isolation rates of Gram-positive (P = 0.173) and Gram-negative (P = 0.920) organisms.
The Spanish annual April-to-June ICU National Nosocomial Infection Surveillance Study (Estudio Nacional de Vigilancia de Infección Nosocomial, [ENVIN]) confirms that multi-drug resistance is an unresolved problem in Spanish intensive care, with worrisome rates of Gram-negative MDR pathogens [ 7].
Then again, the overall MDR rate of gram negative bacteria was 59.3%.
A little drop in isolation rate of gram negative bacteria was noted i.e. from 43% to 41%.
In this study, the overall MDR rate of gram positive isolates (i.e. S.aureus and CNS) was 77%.
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