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Significantly diminished rates of endogenous respiration (−33%) were observed in DJ-1 KO cells compared to the controls.
16, 17 Overnight fasting plasma glucose and insulin concentrations were similar between the two groups (Table 1) as were basal rates of endogenous glucose production (EGP) (Fig. 2E).
They also reported that, as compared with WT hens, R/O hens had attenuated rates of endogenous cholesterol synthesis and a much slower daily turnover of cholesterol.
In a previous study, we demonstrated that experimental differences in hematopoietic cell culture outputs could be recapitulated by varying the secretion rates of endogenous regulators in silico (Kirouac et al., 2009).
Enhanced ER Ca2+ leak would also predict the elevated ADP/ATP ratio and the enhanced rate of ATP utilization we observed in the rates of endogenous O2 consumption (Norris et al, 2010).
Basal hyperinsulinemia and physiological increases in plasma insulin concentration in obese subjects with normal glucose tolerance should therefore be able to overcome insulin resistance in the liver and adipose tissue but not skeletal muscle, resulting in normal rates of endogenous glucose production (EGP) and lipolysis but not glucose disposal.
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rate of endogenous respiration in biofilm, mg-VS dm−3 min−1.
The arrow in (d) highlights that the mesenchymal state can be maintained without EMT-inducing signal S A when the basal production rate of endogenous TGF-β is high.
The rate of endogenous respiration was described as follows [5, 8]: r endo = b endo ρ b X b 1 1 + exp - F RT η (7 where r endo rate of endogenous respiration in biofilm, mg-VS dm−3 min−1 b endo endogenous decay coefficient of active biomass, min−1.
(b) Phase diagram of the circuit shown in (a) in response to an activation signal on SNAIL (S A ) and the production rate of endogenous TGF-β (( {g}_{m_{TGF-beta }} )).
This bifurcation diagrams (Fig. 5c, d) indicate that the 'irreversibility' of mesenchymal phenotype to switch back to a hybrid E/M phenotype depends directly on the production rate of endogenous TGF-β.
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