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Alternatively, rapid radiation is also interpreted as high rates of differentiation in comparison to those of flowering plants.
High levels of Dlk1 promote higher rates of differentiation while low levels trigger more self-renewing cells.
At the cellular level, calvarial osteoblasts isolated from KO mice exhibit delayed rates of differentiation and defects in matrix production and mineralization [11].
The heterogeneity in staining for β-catenin and its intercellular localization may be explained by differences in the individual rates of differentiation of keratinocytes, as well as by region-specific requirements.
The authenticity of antigens recognized by pAb GS is confirmed also by heterogeneity in the intensity and pattern of GS staining between neighboring cells and regions of epidermis and dermis, as well as between cultured human keratinocytes, that might be due to differences in the individual rates of differentiation of these cells.
Our a posteriori analysis of the temporal distributions of metamorphoses (Figure 4) suggests that the early cue had an accelerating effect on the rates of differentiation under both water regimes, but this effect did not last to significantly affect mean time to metamorphosis as a result of full developmental compensation by most of the individuals for the false early information.
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There was no increased activity of BMP-2/6 when compared to BMP-2 in the number of differentiated colonies, rate of differentiation or morphology.
Analysis of BM cells indicated that a faster rate of differentiation of late precursors contributes to the mechanism of action of RAP-011.
The overall fixation index (FST) showed a moderate rate of differentiation at population level (5.9%).
Immunoreactivity against Map2 was detected in >70% of these grafted cells, suggesting a high rate of differentiation toward neurons.
Moreover, the rate of differentiation remains stable at 40% between P30 and P609, which makes is a suitable range to identify potential effects on differentiation of a single gene knockout.
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