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40 First of all, if a larger more definitive trial has to be conducted then a more realistic estimate of the recruitment rate will be needed and more centres should be involved.
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The mix of strong demand and easy money suggests higher rates will be needed to prevent commodities flying again and inflation soaring.
As the continent's populations age, the cost of providing generous state pensions under the current rules will prove insupportable: big increases in tax rates will be needed to balance the books, bigger than most politicians think voters will accept.
Additional reliable PHP data (and, ideally, a refined estimation of position-specific rates) will be needed to clarify the relationship between the likelihood of observation of heteroplasmy in relation to mutation and substitution rates in the coding region, and to determine whether any true heteroplasmic hotspots exist in the coding region.
And as Larry explains, that tale has not been swallowed by the City -- which believes the UK economy is in stronger shape and a rate rise will be needed before 2016.
I take this to mean that the Fed itself suspects strongly that another emergency rate cut will be needed well before the next regular meeting in May.
That suggests more rate cuts will be needed, particularly in Europe.All told, the IMF expects the rich-world economies to grow by only 0.5% in 2009.
First, even some Wall Street analysts who were surprised by Mr. Greenspan's optimism still say more Fed rate increases will be needed in the future to finally slow economic growth to a manageable, noninflationary pace.
At the same time, the implied yield on interest rate futures has risen by approximately 15 to 20 basis points (depending on which timeframe is placed on the market pricing), which means the market is now less convinced that interest rate cuts will be needed over the next six to 18 months.
If the economy looks likely to weaken, further interest-rate cuts will be needed.
Allowing for a 10% drop-out rate, 140 patients will be needed.
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