Mean arterial blood pressure, heart rate, ventilator settings, and lung function variables were recorded at the end of the instrumentation period, at the end of the lavage procedure and every 30 minutes thereafter.
The asynchrony index was defined as the number of asynchronies (wasted efforts, double cycles, premature cycling off ) divided by the total respiratory rate (ventilator cycles + asynchrony events), multiplied by 100.
The asynchrony index (AI) [ 3] was defined by the number of asynchrony events divided by the total respiratory rate computed as the sum of the number of ventilator cycles (patient-triggered) and of wasted efforts: asynchrony index (expressed in percentage) = number of asynchrony events/total respiratory rate (ventilator cycles + ineffective triggering) × 100.
Nosocomial infection rate (ventilator-associated pneumonia, meningitis) was observed in 31.25% of patients (5/16) in the MAT group and in 91% of patients (20/22) in the control group, P < 0.001.
Data were collected on existing hand hygiene compliance rate, ventilator-associated pneumonia (VAP) rate, catheter-related bloodstream infection (CRBSI) rate, catheter-related urinary tract infection (CAUTI) rate, standardized mortality ratio (SMR) and average ICU length of stay in the abovementioned units.
Usage rate of ventilator was 58.32%.
We compare hPSV, hNAVA and hNAVA15, all delivered using the new helmet, with respect to patient's dyspnea, assessed by a visual analogue scale (VASd), arterial blood gases (ABGs), EAdipeak, rate of ventilator pressurization and triggering performance.
The rate of ventilator-associated pneumonia (VAP) per 1000 ventilator days was 13 and 14.6 (p = 0.73) and hospital mortality 27 and 33%, (p = 0.32), respectively [69].
This may be assigned to a higher rate of ventilator-induced lung injury in the conventionally ventilated, surfactant treated animals, where higher ΔP values and tidal volumes compared to the PPVOLC group may led to an increased rate of shear stress to the lung.
Together with a lower use of tracheal intubation and conventional mechanical ventilation, there was a significant decrease in the rate of ventilator-associated pneumonia and a trend toward a lower ICU mortality.
Avoiding tracheal intubation drastically reduces the rate of ventilator-associated pneumonia (VAP), antibiotic use, the time spent under mechanical ventilation, ICU length of stay, and associated mortality [5 9].
