Sentence examples for rate protein binding from inspiring English sources

The paper of J. G. C. van Hasselt et al. on cefazolin pharmacokinetics during pregnancy explores the feasibility to integrate the known physiological changes related to pregnancy (i.c. glomerular filtration rate, protein binding) to predict changes in cefazolin disposition during pregnancy.

k on represents the rate of protein binding to DNA, k off is the dissociation rate of the DNA-protein complex, k m is the rate of transcription, k p the rate of translation, γ m the rate of degradation of mRNA and γ p the rate of degradation of protein.

Interestingly, it has been shown that contrary to its DNA binding capacity, the rate of protein binding of oxaliplatin may be significantly higher than its covalent binding to DNA (in cisplatin adducts, a similarly acting compound, 75-85% of covalent binding occurs with proteins compared with 5-10% in DNA) exhibiting significant differences when compared to DNA lesions [4].

Application of positive potentials greatly increased the rate of protein binding, while negative potentials were used to prevent a weak nonspecific binding, improving thus the S/N ratio.

While the overexpression of GFP-fusion proteins can lead to differences in the rate of protein binding to centrosomes (and we have shown that this is the case for some of these proteins; Conduit et al., Curr.

The blood clearance of 99mTc-MAG3-HBP was delayed because of the high rate of protein binding in blood and the bone/blood ratio of 99mTc-MAG3-HBP was lower than that of 99mTc-HMDP.

Rates of protein binding in mice sera were 86.9% for cefditoren and 91.9% for ceftriaxone.

Moreover, the rate of plasma protein binding was not determined in this patient.

This indicates a superior protein binding rate to nanoparticles with activated carboxyl groups.

The percentage of plasma protein binding rate of DTX (B%) was calculated as:.

ED, combined with highly-sensitive assay, such as high performance liquid chromatography (HPLC) and mass spectrometry (MS), is regarded as the gold standard to determine protein binding rate.