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In comparison to other markers that have traditionally been reported, PCT gives a high rate of specificity for sepsis diagnosis [ 6].
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On a ROC curve, the true-positive rate (sensitivity) is plotted against the false-positive rate (1 - specificity) for each possible threshold of the instrument.
In a plethora of examples, the artificial substitution of one or more amino acids in a polypeptide resulted in a significant increase or decrease of stability, turnover rate or substrate specificity for the enzyme (4).
The ROC curve plots true positive rates (sensitivity) against false positive rates (1 – specificity) for a series of cut-off values, and the area under the curve (AUC) indicates the discriminative ability of a test [ 48].
This study included 973 patients with 1029 nonpalpable breast lesions and showed a sensitivity rate of 97% and a specificity rate of 99% for stereotactic-guided LCNB.
The true positive rate (sensitivity) is plotted in function of the false positive rate (1-specificity) for different cut-off points.
In ROC curves, the true positive rate (sensitivity) is plotted as a function of the false positive rate (1-specificity) for different cutoff points.
The true positive rate (sensitivity) as function of the false positive rate (1-specificity) for different cutoff points was plotted for both the across experiment comparison and our integrated approach using the R-library ROCR.
We next plotted the true positive rate (sensitivity) as function of the false positive rate (1-specificity) for different cutoff points for both our integrated approach and the across experiment comparison (Fig. 5).
In countries such as Indonesia, with high background rates of LTBI, test specificity for TB disease will likely be low.
In countries such as Indonesia, with high background rates of LTBI, test specificity for TB disease is low [19].Our study was not designed to evaluate the QFT-IT in the diagnosis of active TB disease in TB suspects [17].
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