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This model predicted that as the rate of paralysis becomes slower the estimated therapeutic windows of impermeable inhibitors become longer.
The rate of paralysis of the RLN was calculated on nerves at risk for hypocalcemia (n = 890) in patients undergoing bilateral procedures or unilateral procedures if they had previously undergone a contralateral operation (n = 321).
Accordingly, the rate of paralysis and death due to polio infection also increased during this time.
The higher rate of paralysis with PVL strategies may be related to higher rates of respiratory acidosis and ventilator dysynchrony.
Aldicarb, an acetylcholinesterase inhibitor, causes progressive paralysis in a population of worms and the rate of paralysis is indicative of the total amounts of neurotransmitter released at the neuromuscular junction.
The rate of paralysis within the daf-2 RNAi-treated animals was 9% (Fig. 3A).
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Following the rates of paralysis, we found that the knockdown of either one of these transcription factors abolished the NT219-mediated protection from Aβ aggregation (Fig. 3C).
Similarly, we also found that the rates of paralysis within daf-16 RNAi-treated Aβ worm populations that were either treated with NT219 or exposed to vehicle were nearly identical (Fig. S5).
Aβ worms that were hatched and developed on daf-2 RNAi expressing bacteria transferred away from daf-2 RNAi onto daf-16 RNAi bacteria at either day 1, 5 or 9 of adulthood (daf-16 RNAi reduces mRNA levels within 3 h, Supporting Fig. S4A) and the rates of paralysis within the worm populations were recorded (Fig. 4A).
It turned out that the vaccine caused Guillain-Barr?yndrome, a rare paralytic disease similar to polio, with a 5percentt fatality rate and a 10percentt rate of permanent paralysis.
The rate of onset of paralysis with IVDD has not proven to be predictive of outcome in two studies [ 1, 15].
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