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The high rate of exclusions based on laboratory parameters raises some questions: Could there have been un-diagnosed co-morbidities?
First, our study had high rate of exclusions due to absent x-rays.
The rate of exclusions tended to be higher in the NW than in London, although this difference was small for asthma, COPD and diabetes.
Remarkably, besides an unexplained higher rate of exclusions in females than in men, there was no significant difference in the initial patients' characteristics between the eligible and non-eligible patients.
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According to the UN children's agency, Unicef, Dalit girls have the highest rate of exclusion from primary school in India and the highest dropout rates, a tendency that will not be curbed by legitimising child labour in their free time.
In the seven selected RCT, the rate of exclusion ranges from 0.3%[47]to84%[43]% [43].
This strategy would be particularly important for migraine, a condition where patient defeatism and unawareness of the current effective treatments of migraine might be at least in part responsible for the high rate of exclusion from medical care.
These percentages were calculated for each pathology (Table 4), showing that some pathologies had a high rate of exclusion (e.g., pneumonia/TB, splenomegaly, uterine myomatosis, ovarian cyst, cirrhosis, gastritis/PUD).
This prompted us to separate the investigation of the younger (65 84 years old) from that of the older (85+) persons (which began in May 2007), since the expected rate of exclusion would be quite different in the population above or below 84 years old.
In the seven selected RCT, the rate of exclusion ranges from 0.3%% [ 47] to 84%% [ 43].
Data of unselected population-based studies suggest a high rate of exclusion from clinical trials in older age.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com