Sentence examples for rate of depolarization from inspiring English sources

The rate of these contractions is governed by the rate of depolarization of the muscle cell membrane.

Further analysis showed that day 20 RhiPSC-CMs have MDP (maximal diastolic potential) of −55 mV~−47 mV and dV/dtmax (maximal rate of depolarization) of 16~19 v/s (Fig. 4b), which is comparable to the reported parameters for human iPSC-derived immature cardiomyocytes8,34.

The results suggest that in pathological substrates that are arrhythmogenic, maintaining cell size during remodeling of gap junctions is important in sustaining a maximum rate of depolarization.

Depending on the concentration, local anesthetics decrease Na influx by blocking Na channels, and decrease the rate of depolarization in nerve fibers and other excitable cells.

In animal models, methadone has been shown to affect the action potential by decreasing the rate of depolarization and increasing the action potential duration.

They block the fast sodium channels in the fast-conducting tissue of Purkinje fibers and ventricles leading to a reduced rate of depolarization as well as the effective refractory period and action potential duration (https://www.openanesthesia.org/local_anesthetics_systemic_toxicity/).

Electrophysiological parameters, such as the action potential duration (APD), rates of depolarization and repolarization and beating frequency were assessed.

As shown in Figure 8A, the majority of selected cardiomyocytes displayed action potentials (APs) with relatively depolarized maximal diastolic potentials (MDPs, >−45 mV) and slow maximal rate of AP depolarization (Vmax, <5 V/s). Figure 8B shows that 10 20% of cardiomyocytes, however, possess MDP<−45 mV and faster Vmax (>5 V/s).

The rate of spontaneous depolarization is an important determinant of heart rate.

This decreases the resting potential of the myocytes of the SA node while increasing the rate of diastolic depolarization.

Conversely, stimulating the parasympathetic nervous system (vagal nerves to the heart) increases the resting potential and decreases the rate of diastolic depolarization; under these circumstances the heart rate slows.