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Zerbo et al. [30] concluded that due to the absence of osteoinductive properties of TCP, the rate of bone formation was delayed in comparison with autogenous bone grafts.
Sánchez et al. [31] investigated whether the addition of PRP to xenogeneic bone grafts (demineralized freeze-dried bone graft) would increase the rate of bone formation.
The model predicts the in vivo rate of bone formation within the scaffold, the scaffold degradation and the interaction between the implanted scaffold and the surrounding bone.
Within the trabecular compartment, the rate of bone formation close to the implant was transiently higher than far from the implant mainly due to an increased mineral apposition rate which indicated a higher osteoblastic activity.
Conversely, in cortical bone, the higher rate of bone formation close to the implant compared to far away was mostly related to the recruitment of new osteoblasts as indicated by a prevailing mineralizing surface.
Therefore, quantification of the rate of bone formation was not possible.
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We examine appropriate vectors, safety issues, and rates of bone formation.
Thus, it may be possible to design HA coatings that induce optimal rates of bone formation and degradation specifically tailored for different applications in orthopedics and dentistry.
The bone serves as the predominant repository of calcium in the body, and hence, the relative rates of bone formation and resorption influence calcium balance [ 8].
Hyperthyroidism is accompanied by osteoporosis or osteopenia with increased rates of bone formation and bone resorption with predominance of resorption [ 2, 3].
Thus, the CS mice have a reduction in osteoblasts that is associated with decreased rates of bone formation and mineral apposition, and this lack of bone calcium deposition may account for the observed hypercalcemia, decreased circulating PTH concentrations, and hypercalciuria.
More suggestions(15)
assessment of bone formation
extent of bone formation
percentage of bone formation
degree of bone formation
rate of spine formation
rate of bone resorption
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rate of bone healing
rate of tooth formation
rate of bone loss
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rate of star formation
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