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This corresponds to a constant underlying rate of beginning implementation, once the effects of the different milestones are allowed for.
Rates of beginning implementation are calculated relative to the rate of beginning HepB implementation in high income countries in the absence of any of the facilitating milestones.
Plots of the cumulative baseline hazard over time were used to assess time trends in the underlying rate of beginning implementation, allowing for the covariates of income level and milestones described previously.
Availability of an improved intervention seemed to have little effect on the rate of beginning implementation (relative uptake rate 0.86; CI 0.62-1.18).
Plots of the rate of beginning implementation (i.e. rate of adoption; cumulative baseline hazard from the Cox model) for analysis including only high income countries, suggested a more or less linear increase with time.
There was a highly significant difference between level of income of countries and the rate of beginning implementation (LRS 27.2; 3 d.f.; P < 0.0001), this difference being almost entirely accounted for by the difference between high income countries and the others.
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Cox proportional hazard models were used to compare the rates of beginning implementation of interventions between countries, as functions of the intervention and income group of the country.
There was very little difference in rates between the different categories of middle income countries, or between middle and low income countries (Table 6); each of these categories was associated with rates of beginning implementation only just over half that of high income countries.
There were significant statistical differences in rates of beginning implementation between interventions relative to hepatitis B vaccine in high income countries (likelihood ratio statistic (LRS): 30.6; 6 degrees of freedom (d.f).; P < 0.001, adjusted for effects of income level and of the different milestones) (Table 6).
In anticipation of a recovery in airline demand, Airbus said that it planned to step up production of its popular single-aisle A320 jet to 36 planes a month from the current rate of 34, beginning in December.
Underscoring its confidence in a recovery in airline demand, Airbus said that it planned to step up production of its popular single-aisle A320 jet to 36 planes a month from the current rate of 34, beginning in December.
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