The high response rate minimised the risk of bias due to the population not being representative of the target population.
The high response rate minimised the potential for responder bias caused by those least in favour of data publication being less likely to respond.
A list of potential cellular objectives (growth rate, minimising the sum of fluxes in the network, maximising ATP production …) and experimental flux measures are provided in an additional input file.
"In part that is because rates of transition into jobs, even for those who have been unemployed for more than a year, have been sustained at high rates, minimising the extent of skill atrophy.
The high follow-up rates minimised the possibility of selection bias.
Therefore, these loci may have relatively low mutation rates, minimising the probability of frameshifts arising.
Ways to improve response rates, minimise survey response bias and item non-response, within a given budget, have not previously been addressed in the same study.
The study is designed to minimise the time burden placed on both GPs and practice staff in order to increase general practice recruitment rates, minimising recruitment bias of practitioners and subsequently patients.
We believe the simplicity of the study design incorporating recruitment at/near delivery, ascertainment of infant exposure status at day 0 (delivery) then ascertainment of the primary outcome from administrative data sets––will maximise maternal participation rates, minimise drop out and thus minimise the risk of response bias.
This study highlights an important challenge for trialists planning to recruit patients in professional-cluster trials undertaken in Australian primary care; namely, minimising the impact of the trial on practice staff time, maximizing the recruitment rate, and minimising the chance of selection bias.
