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Thus, by letting the parameters defining production rate and decay rate mediate genetic variation in our genotype-phenotype models we account for a whole range of different, and possibly still unrevealed, mechanistic processes responsible for this variation.
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While Adh1p, for example, shows evidence of nutrient mediated post-transcriptional regulation, another alcohol dehydrogenase (Adh3p) shows strong growth rate mediated regulation.
The new birds birth rate is expressed by the parameter Λ. Susceptible birds die at the rate μ and infected birds die at the rate (mu+r), where r is the additional death rate mediated by avian influenza.
In our particular case this means that for certain parameter values of the transcription rates s1 to s4 the Nanog concentration stabilizes either at a low level, i.e. close to a basal transcription rate mediated by the Oct4-Sox2 corplex, or at a high level with substantial contribution from the auto-regulation.
Findings supported the hypothesis that autonomic activity (heart rate) mediates the effect of the expressive writing condition on self-reported physical symptoms.
The reduction rate mediated by the combinatorial approach was higher compared to that achieved by either of the 2 approaches alone, and these obvious additive effects became most pronounced when the GCV concentration was low.
Taken together, the difference in CTD zippering energy contributes to the large variation in the fusion rate mediated by SNARE complexes and indicates a different number of SNARE complexes required for different fusion processes in vivo.
In C. briggsae, analysis of recombinant inbred lines derived from crosses between divergent strain pairs found that cytonuclear epistasis and differences in development rate mediated by particular alleles or allele combinations are factors (Ross et al. 2011).
This effect will tend to counter the effect of growth rate mediated length-biased sampling, and the net effect on survival and prognosis will depend on the relative strengths of these opposing influences.
In murine models of sepsis due to caecal ligation and puncture, administration of EPO post insult is associated with a fourfold improvement in the glomerular filtration rate mediated by protective effects on superoxide dismutase [ 69].
How does perceived psychosocial stress differ between single and partnered mothers? 2. Does psychosocial stress account for moderate and heavy smoking pattern and if so, does its effect hold for both single and partnered mothers? 3. Is single mothers' higher smoking rate mediated by psychosocial stress?
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