Enriched GO terms for the HLH-1 ChIP-chip peaks included embryonic development, larval development, reproduction, regulation of growth rate, locomotion, growth, and body morphogenesis (Figure 5B), consistent with the role of HLH-1 in embryonic development and bodywall myogenesis.
Thus, despite a moderate increase of CS rate during locomotion, CS synchrony was significantly disrupted during self-initiated locomotion in tg/tg mice.
Morphological defects such as edema, body curvature, delayed growth, decreased heart rate and locomotion were observed for each of the compounds tested, often at sublethal concentrations.
Unoriented responses include kineses undirected speeding or slowing of the rate of locomotion or frequency of change from rest to movement (orthokinesis) or of frequency or amount of turning of the whole animal (klinokinesis), the speed of frequency depending on the intensity of stimulation.
Thus, this study evaluated the effects of GO exposure (at 5, 10, 50 or 100 mg/L) during six consecutive days on mortality, hatching, spontaneous movement, heart rate, morphology, locomotion behavior, acetylcholinesterase (AChE) activity, dopamine levels and relative gene expression of developmental neurology-related genes using zebrafish larvae.
Under these conditions, LSJ1 moved faster than N2 at 21% O2 and reduced its rate of locomotion as O2 fell to 19 and 17%, although not as dramatically as when food was present.
While there is some overlap between these studies of Bertil Fredholm's group [30], [31] and our present data, the main differences between both studies are the mechanisms of adenosine receptor mediated alterations in blood pressure, heart rate and locomotion.
Ethanol causes a dose-dependent decrease in the rate of locomotion of C. elegans.
First, although all granule cells increase their firing rate during locomotion, the relative increases in firing rate span a wide range.
It has been proposed in a wide range of animal models that there is an inverse relationship between longevity, metabolic rate, and locomotion.
ST3, mitochondrial State 3 respiration; ST4, mitochondrial State 4 respiration; BW, body weight; GLY, glycogen; TAG, triacylglycerol; GLYC, glycerol; MR, metabolic rate; LC, Locomotion; FT, competitive fitness; CL, copulation latency; SR, starvation resistance; CC, chill-coma recovery; LS, lifespan.
