Sentence examples similar to rate limiting event from inspiring English sources

It is also believed that the detachment of cytochrome c from the inner membrane and its release into the cytosol is one of the rate limiting events in the execution of the apoptotic program [ 28].

It subsequently directs the selection of in vitro assays for rate-limiting events in the biological network, to feed parameter tuning in the model, leading to prediction of the toxicological outcome.

It should be realised however that preceding the activation of the local immune system, some possibly rate-limiting events need to be executed.

Together with loss of the homologous chromosome 3p allele (3p LOH), VHL mutations are rate-limiting events in the carcinogenesis of clear-cell RCC [ 3, 4].

An analysis of dose-response concordance should enable the identification of a rate limiting key event for the MOA and whether any one key event is the critical determinant of the response.

Altogether, these data suggest that activation of the K-Ras signaling pathway is an essential rate-limiting event during lung tumorigenesis.

Throughout the wound healing process, cell migration is a rate-limiting event.

Metastatic seeding is the rate-limiting event for carcinoma progression [ 39].

The time to photobleaching for individual EGFP molecules was dominated by a single rate-limiting event, in agreement with previous report [ 26, 37].

It is likely that the rate-limiting event which increases cellular and hence organism vulnerability to death may vary according to circumstances.

Biallelic von Hippel-Lindau (VHL) gene defects, a rate-limiting event in the carcinogenesis, occur in approximately 75% of sporadic clear-cell Renal Cell Carcinoma (RCC).