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Eight of the nine rats had previously taken part in Experiment 1. Four rats were trained on the eight-arm spatial working memory task, and five were trained on the one-arm control task, including the one rat with bilateral dHPC CPEs.
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The pharmacokinetic effects of EIDD-1723 on morphological and functional outcomes in rats with bilateral cortical impact injury were evaluated.
Ovariectomized female rats, with bilateral cannulae directed toward the ventromedial nucleus of the hypothalamus (VMN), were hormonally primed with 10 μg estradiol benzoate and 500 μg progesterone.
We previously reported that adult male rats with bilateral induced microgyria exhibit deficits in rapid auditory processing, which appear similar to auditory processing deficits seen in individuals with developmental language disabilities.
To study the biological functions of salivary nitrate and nitrite in stress protection, we further carried out a water-immersion-restraint stress (WIRS) assay in male adult rats with bilateral parotid and submandibular duct ligature (BPSDL).
The results showed that rats with bilateral aspiration lesion of the seizure controlling substrate, area tempestas (AT) in the piriform cortex, displayed marked anticonvulsant effects, whereas such effects were not seen when substantia nigra was destroyed.
Specifically we investigated brain activation in response to CRD between rats with bilateral amygdala implants of CORT and age and weight-matched CHOL control rats.
In the current study we investigated total brain activation in response to 40 and 60 mmHg of CRD in anesthetized rats with bilateral implants of CORT placed stereotaxically on the dorsal margin of the amygdala (Figure 2).
Two cohorts of rats, both including rats with bilateral hippocampal lesions, were tested on object recognition in the dark.
Retention of reversal learning: Rats with bilateral lesions of the NAc core and shell did not show any difference to retain the reversals compared with sham controls.
However, tail flick latency did not increase when spinal ketamine was administered to rats with bilateral dorsal funiculus (DLF) lesions in a system where morphine was effective.
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