IN order to test for functional competence in thin pieces of isolated tissue containing muscular elements, such as the skin of the rat (which contains smooth muscle and a sheet of skeletal muscle known as the panniculus carnosus)', a bath was devised in which the muscles could be excited directly or indirectly by transmural stimulation1.
Age-related changes in the densities of immunoreactive terminals were also observed within the dorsolaterateral nucleus (homologue of Onuf's nucleus in humans) of the rat, which contains somatic motoneurons that innervate the external urethral sphincter and ischiocavernosus muscles.
The results demonstrated that SY3 at doses of 20, 40 and 80 mg/kg behaved remarkable action on sleep architecture of rats, which contain the increase of total sleeping time, the rate of deep slow wave sleep (SWS) and mean episode duration of deep SWS, and the decrease of the latency of deep SWS.
Figure 6F right panel shows histological evidence of tendon pathology in 12-week HRHF rats as increased rounded cells (including tenocytes) in the endotendon, and increased disorganization and separation of tendon fibrils, compared to NC rats, which contained only slender/elongated tenocytes and closely packed parallel fibrils.
Because certain neuronal populations [such as dopaminergic (DA) neurons found in the brain striatum] are especially vulnerable to OS (Mattson 2001), the neurotoxicity of P25 was studied in the N27, an immortalized rat DA neuronal cell line (Zhou et al. 2000) and complex CNS cultures of embryonic rat striatum, which contains high numbers of DA neurons (Maier et al. 1994).
We isolated rat MIF cDNA, which contains an open reading frame of 345 base pairs that encodes 115 amino acid residues.
For the construction of NL1 expression plasmids, the ectodomain portion of rat NL1 (residues 31 638), which contains 9 amino acid splice B insertions, was amplified from pCMVNL1-14 (a gift from T.C. Südhof) [37] and fused to the C-terminus of a human growth hormone (hGH) minigene using a pSGHV0 vector [38], thus resulting in the construct hGH_NL1_B+.
The CALUX® assay is based on a genetically modified H4IIE rat hepatoma cell line, which contains the firefly luciferase reporter gene under the transcriptional control of AhR.
We constructed a cytogenetic map of the Japanese four-striped rat snake, which contained 183 genes.
The selectivity and accessibility of the pendent galactose residues was demonstrated by the culture of primary rat hepatocytes, which contain a cell-surface asialoglycoprotein receptor (ASGPR) that can specifically bind to galactose for enhanced cell adhesion and function.
The selective ALDH3A1 inhibitor CB25 [28] inhibited aldehyde dehydrogenase activity in homogenates of rat eyes, which contain large amounts of ALDH3A1 [35], with an IC50 of 5.7 ± 2.2 μM but had no effect on GTN- or DEA/NO-induced relaxation of rat aorta or coronary arteries from pigs and cows (data not shown).
