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Each object was concurrently available for the rat to explore for a total of 1 min (Table 1A).
The novel object recognition test measures the natural propensity of a rat to explore a novel versus familiar object.
We performed multiple sequence alignment of Nrf2 and Nfkb1 genes in five mammalian species – human, chimpanzee, dog, mouse and rat – to explore conserved biological features.
Each object was concurrently available for the rat to explore for a total of 1 min. The central sliding door was then raised to reveal two more objects (the now familiar object B2 vs. novel object C1) at the opposite end of the maze for exploration by the rat (Trial 2).
For every trial, the rat was allowed to forage throughout the whole environment for 15 min. Cooked rice grains were scattered throughout the trial so as to motivate the rat to explore every region of the environment evenly and without depleting any of the compartments.
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We plan to change the dosage and frequency of IS and use different sexes of rats to explore the aetiology of this comorbidity.
13550_2014_64_MOESM1_ESM.docx Additional file 1 Supplementary material to the manuscript by Tóth et al. Additional PET experiment using P-gp knockout and wild-type rats to explore the contribution of the ABC transporter P-gp on the brain uptake of [11C]AZ10419369.
To study the expression of ADAMTs-5 and TIMP-3 in temporomandibular joint osteoarthritis (TMJOA) model rats, to explore and confer the possible effects of ADAMTs-5 and TIMP-3 involved in the degradation of the early stage of OA.
Continuing this line of investigation, two subsequent studies by the same group used relatively similar NaHCO3 dosing and high-intensity training protocols on rats to explore fibre-type dependent protein expression associated with H+ removal during rest and exercise [90, 91].
The test relies on an innate tendency of rats to explore a novel environment [ 48].
We employed streptozotocin- (STZ-) induced diabetic rats to explore the ability of learning and memory by the Morris water maze test.
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CEO of Professional Science Editing for Scientists @ prosciediting.com