Sentence examples for rat study in from inspiring English sources

The short-term (i.e., 1 30 days) human no observed adverse effect level (NOAEL) for a dermal CPF exposure was set by the U.S. Environmental Protection Agency EPAat at 5 mg/kg/day based on a rat study in which plasma BuChE and RBC AChE were inhibited 45%and16%6%, respectively (U.S. EPA 2006).

This has also been demonstrated in another rat study in which treatment with amiodarone reduced the expression of two TRβ1-dependent genes (as evident from a lower LDL receptor protein concentration and a lower iodothyronine-5′-deiodinase-activity in liver), whereas treatment with dronedarone did not [ 23].

Neil Grunberg, a behavioral neuroscientist at the Uniformed Services University of the Health Sciences in Bethesda, Maryland, was the first to prove, through rat studies in 1982, that nicotine causes a decrease in appetite.

The dose of lovastatin was based on rat studies in ADPKD [ 12] and experimental nephrotic syndrome [ 16].

This is in contrast to the rat studies, in which animals subjected to early-life food deprivation were significantly lighter than control animals at the time of study (Qasem et al., 2012; Vickers et al., 2000).

Many of the WF toxicity studies that have been conducted on GM crops have been 28- or 90-day subchronic rat studies in which the GM food was administered by incorporation into the diet.

Rat studies in brain ischemia have found a role of postsynaptic density (PSD), proteins, specifically PSD-95, in potentiating NMDA function and signaling to nitric oxide synthase resulting in chronic and neuropathic pain.

For the purpose of discussing the timing of exposure and outcome measurements in the rat studies in an integrated fashion, the day of mating and succeeding gestational days have been corrected to GD 0 for Moxon (2002).

Manual scoring of behavior, based on visual observation of the video, revealed that rats studied in the dark period often exhibited vigorous exploratory behavior (score of 5) during the micturition events (average score: 2.12±0.57; Video S1).

In contrast to the reports in rats, studies in humans using exogenous glucocorticoid administration suggest that negative feedback may be reduced over the reproductive cycle.

This mechanism was first proposed and explored in rat studies conducted in the 1980s.