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In contrast, three other rat strains tested - Lewis, Wistar Furth, and Brown Norway - were found to be resistant to vasculitis development, although similar levels of anti-human MPO antibodies were detected [ 59].
Instead, the KFRS4 strain of dumbo rats exhibits a 5777-bp deletion approximately 79 kb distal to the end of the final Hmx1 exon that is not found in any of 137 other rat strains tested.
Neither the correlation analysis nor the principal component analysis provided convincing support for the notion that the three tests measure the same underlying trait in the rat strains tested.
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The in vitro intracellular replication profile of the Francisella strains tested corresponded to in vivo susceptibility of Fischer 344 rats to pulmonary challenge.
influenzae strains tested.
pneumoniae references strains tested.
Our objective was to characterize individual differences in fear conditioning and extinction in an outbred rat strain, to test behavioral predictors of these individual differences, and to assess their heritability.
It is unlikely that these differences were due to differences in rat strains or test procedures because male wistar rats were used for all these studies and the same test procedure was used to assess ICSS thresholds.
The time spent in the center may be less sensitive than the time spent in the corners as index of emotional reactivity or anxiety, because the time spent in the center decreased to near zero in most rat strains across testing days, whereas the time spent in the corners increased and the difference between strains increased with repeated testing (see also Fig. 3a).
Though both the hotplate and tail-flick involve thermal nociception, this difference may be related to methodological differences including rat strain, body part tested, diet composition, stimulus strength (latencies are generally longer in our study), and length of dietary treatment (12 wk in Ziegler et al).
Following the recommendation that emotional reactivity should be evaluated in a battery of tests, not just a single test [ 81, 82], we tested the four rat strains in the OF, the EPM, and the cLDB.
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