Sentence examples for rat strains for from inspiring English sources

These results can be used to guide the choice of appropriate rat strains for future studies of the genetic architecture of obesity and body size.

Additional file 6: Figure showing the subchromosomal pattern of similarity and divergence between the 40 + 1 rat strains for all autosomes.

The comparison between inbred rat strains for hepatic and renal gene expression, which was repeated on Affymetrix, Illumina and Operon microarrays, showed that the kidney appeared to produce less reproducible data, perhaps due to morphological heterogeneity of this organ.

Genotyping commonly used rat strains for newly identified SNPs revealed that 84% of SNP-alleles (and 87% of all genetic variation) occurring between BN and a single wild individual is also represented in one or more laboratory strains.

We used the new sequence data from the 27 rat strains for two main purposes: to provide a firm foundation for understanding the phylogenetic history of the laboratory rat and to give new insights into the genetic and pathophysiological basis of the disease phenotypes for which the various rat strains were selected.

Between-group differences in reported values may be related to differences in rat strains (for example Sprague Dawley vs. Wistar), methodological differences, or differences in the severity of diabetes or the time that measurements were made after the onset of disease.

In addition, we have described the effects of NTN on a double congenic rat strain for chromosomes 13 and 16 (WKY.L Crgn1,2) generated by introgressing LEW Crgn1 and Crgn2 into the genetic background of the WKY strain.

Many studies have investigated differences in cardiovascular disease-related phenotypes between different mouse and rat strains (see, for example, [ 196 , 197].

To our knowledge, no direct comparisons of rat strains contrasting for their emotionality levels have been carried out in the COT, which would shed some light on the psychological significance of this test.

Although the reasons are unclear, differences in rat strains cannot account for the divergent results because conflicting results have been documented in all rat strains used to date.

Two inbred rat strains frequently used for studies on T2DM include the nonobese Goto Kakizaki (GK) rat and the obese Zucker fatty diabetic (ZDF) rat.