Sentence examples for rat skin with from inspiring English sources
Their promoting activity on the percutaneous absorption of five model drugs, 5-fluorouracil (5-FU), isosorbide dinitrate (ISDN), lidocaine (LD), ketoprofen (KP), indomethacin (IM), which were selected based on their lipophilicity represented by log KO/W, was tested in vitro across full thickness rat skin with each of the evaluated drugs in saturated donor solution.
The first support for this hypothesis came from the incubation of mitochondria isolated from rat skin with 7DHC, which showed that 7DHC is metabolized to 7DHP.
Frozen human brain 9-L tumors grown under rat skin with Institutional Animal Care and Use Committees (IACUC) approval were kindly provided by the Brain Tumor Research Laboratory at the Johns Hopkins University.
The carcinogenic air pollutant 2-nitrofluorene was reduced to the corresponding amine by the microsomal fraction of rat skin with NADPH and by the cytosolic fraction with 2-hydroxypyrimidine or 4-hydroxypyrimidine or hypoxanthine under anaerobic conditions.
The tips of DMNs could be dissolved in rat skin within 1 h with a drug delivery efficiency of 63.8 ± 2.0%.
In comparison, PEU-SF was more homogeneous with the surrounding rat skin, accompanied with some angiogenesis).
Confocal laser microscopy of rat skin treated with sodium fluorescein labeled NLC showed a significantly (p < 0.001) deeper penetration (187.34 μm) as compared with the conventional gel (19.25 μm).
Despite its potential for promoting the keratinocyte differentiation, in our study, the epidermal thickness of Brn2-injected rat skin significantly increased with the increased differentiation in the spinous and granular layers.
Our study shows that production of GS by skin is developmentally regulated and that the dynamics of postnatal differentiation of GS in human and rat skin is comparable with age-dependent changes in GS expression in human and rat skin (Table 2).
Lockley et al. (2005) observed ADH/ALDH activities in whole and dermatomed rat skin cytosolic fractions with rates that were greatest for 2-butoxyethanol > 2-phenoxyethanol > ethylene glycol > 2-ethoxyethanol > ethanol and dermatomed skin cytosol with approximately twice the specific activity of whole rat skin.
The bullet-shaped MNs provided an optimal geometry for mechanical interlocking, thereby achieving significant adhesion strength (~ 1.6 N cm− 2) with rat skin.
