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Functional studies in the GK rat show a reduction in insulin granule fusion [ 17].
The corresponding regions in mouse and rat show a strong conservation in relative position, suggesting the putative promoter regions.
Previous work suggests that mouse and rat show a high degree of DNA sequence homology with the Chinese hamster [ 15] and several transcriptomic studies have employed a comparative approach to examine and annotate CHO sequence data [ 12, 16].
It is interesting to note that the IgC2 domains of CEACAM1 orthologs from human, cattle, mouse and rat show a higher degree of sequence conservation than the amino-terminal IgV-like domain [ 30, 78].
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b CP-treated rat showing a marked increase in Bcl-2 immunoreactivity in the hepatocytes (brown color).
Any rat showing a decrease in mean grip score is at increased probability of DCS.
If the ratio is positive, the rat shows a preference for novel objects.
Pancreatic islets isolated from rats show a circadian rhythm in insulin secretion93.
Ribeiro say their results show clear evidence of criticality throughout this cycle (although the same rats show a different pattern when anaesthetised).
Indeed, although some discrepancies have been reported27,31,32,33, both mice and rats show a dorso-ventral distribution of various types of interneurons.
Studies on rats show a median lethal dose (LD50) as low as 180 mg/kg for some Mo compounds.
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