The properties of human benign prostatic hyperplasia (BPH) and rat prostate were compared after culture in the absence of insulin and testosterone.
ERβ was originally cloned from rat prostate, which is one of the most ERβ dense in the body.
Costello et al. [ 51] also found that citrate oxidation in rat ventral prostate was stimulated by testosterone.
Testosterone-induced DNA synthesis in cultured rat ventral prostate was used to compare the direct effects of Estracyt and Emcyt with that of their metabolite, estramustine, and their carrier-hormone, oestradiol-17 beta on prostatic growth.
PB, a rat prostate protein, is also expressed selectively in prostate [ 10].
Mice and rat prostate glands are divided into multiple lobes, where each lobe is histologically distinct.
Absolute quantification of mRNA levels of 5 α-R1 and 5 α-R2 in rat prostate tissues was performed by real-time PCR using the Techne Quantica real-time PCR system with SYBR Green PCR Master Mix (Promega).
Cell lines derived from the Dunning rat prostate carcinoma were obtained from Dr John Issacs, Johns Hopkins University (Baltimore, MD, USA) (AT2.1, AT3.1) and maintained as described previously (Isaacs et al, 1986).
The prostate is your friend.
