The acute administration of cocaine (5-20 mg/kg) to rats produced a dose-dependent elevation in both serum corticosterone and plasma adrenocorticotrophic hormone (ACTH).
Daily administration of dicyclohexylamine (DCHA), an inhibitor of spermidine synthase, to neonatal rats produced a dose-dependent depletion of brain spermidine, accompanied by a rise in putrescine and spermine.
Injection of the patient's serum into female rats produced a significant fall in leukocyte (P less than 0.02) and platelet counts (P less than 0.005), but no significant decrease in hematocrit.
Of note, Dex-pretreated rats produced a potent, dose-dependent diuresis during 12-hour water-access period (Fig. 1C).
In the extinction trial, however, HAB rats produced a larger number of faecal boli compared with LAB rats (HAB, 3.8 ± 0.3; LAB, 1.9 ± 0.6) (P<0.65).
Induction of short time (60 min) Isc, in control rats, produced a loss in the glomerular eNOS and an increase of its interstitial expression (c).
The O3-tolerant rats produced a unique cytokine profile that is comparable with an influx of TH2 cells and eosinophils and the development of airway hyperresponsiveness.
Inhalation of > 95% oxygen for up to 72 hr in Sprague-Dawley rats produced a marked increase in lung weight and an accumulation of fluid in the thorax when compared with air-breathing controls.
Two-year feeding studies of PFOS in rats produced a modest, largely benign, liver tumor response in the high-dose group (20 ppm PFOS in feed), which likely occurred through nongenotoxic mechanisms (Seacat et al. 2002a).
The acute and daily administration of Maca in sexually experienced male rats produced a small change in ejaculation latency and postejaculatory interval and these changes disappeared with chronic treatment.
