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Consistent with observations in rat, our data in mice show that Gh is expressed in the hippocampus in a hormone-dependent manner; this may be an important aspect of learning and memory mediation by Gh.
In the rat, our data now suggests a specific functional role for the FOF in decisions driven by accumulation of evidence: the FOF appears to be a requisite component of the output pathway of an evidence accumulator with a long time constant (>0.24 s).
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While genes related to tumor growth and metastasis were downregulated by Tamoxifen in FO fed rats, our data also point to a potential immunologic mechanism of tumor escape from the combined intervention.
In OVX rats, our data indicate that a single BPA dose of 40 μg/kg, below the U.S. EPA reference dose and only 4-fold higher than the European Commission TDI safe daily limit, is sufficient to significantly impair the PSSD response to maximal 17β -E2 stimulation.
In rat ipRGCs, our data indicate that Ih has an activation time constant near 900 ms for a voltage step to −123 mV and a V1/2 of approximately −100 mV.
Here, we investigated whether the densities of OLs and OPCs were altered in cortical lesions of early and late-stage MS. Furthermore, we examined the efficacy of OPC and OL recruitment in cortical demyelinated lesions in a rat model of MS. Our data indicate that NogoA+ OLs as well as Olig2+ OPCs are substantially reduced in chronic, but not early cortical MS lesions.
In addition, behavioral abnormality and level of tyrosine hydroxylase (TH) immunohistochemistry were stable from 6 to 18 weeks after the unilaterally 6-OHDA-lesioned rats (our personal data), indicating that a period between PET scanning and sacrificing, within 6 days, may not be critically influenced on the results using the animals within 18 weeks after the lesion.
KIT is expressed in both developing and adult taste buds in the rat [47], and our data shows that both KIT and its ligand are expressed in primate taste buds pointing to the presence of taste progenitor cells.
The behavioral metrics with the potential to associate with lumbar radiculopathy in the rat, based upon our data, are summarized in Table 2.
This is the first report of enzootic A. cantonensis infection in Jamaican rats and snails; our data show that the range of the parasite extends to another Caribbean country outside Cuba, the Dominican Republic, and Puerto Rico (3 – 5 ).
Also consistent with our rat data and with a good analogy between rat and primate PPC, a preliminary report has suggested that unilateral primate PPC inactivations have no effect on accumulation of evidence trials, while causing an ipsilateral bias on free choice trials (Yates et al., 2014).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com