Sentence examples for rat models using from inspiring English sources

We firstly established AD rat models using intracerebroventricular injection of Aβ1-42.

In the meantime, efforts were still made to refine cholinergic-based rat models using 192 IgG-saporin, a toxin linked to an immunoglobulin that selectively targets cholinergic neurons [ 32].

These studies were confirmed in mouse and rat models using metformin treatment doses that achieved similar plasma concentrations to those observed in type 2 diabetes patients treated with metformin [ 68].

Rat models using KA or pilocarpine to induce SE report excitotoxic or apoptotic cell death of pyramidal neurons in areas CA3 and CA1 and dentate hilar neurons in the hippocampus (Turski et al., 1983; Ben-Ari, 1985; Leite et al., 2002; Pitkanen et al., 2006).

A representative analog was established to cause significant appetite suppression and reduction in body weight gain in industry-standard rat models used to develop new therapeutics for obesity.

Investigation of clearance and posttransfusion recovery in a rat model using fresh and stored human RBCs.

The in vivo subacute toxicity of cordycepin was evaluated in a rat model using oral administration.

Intravenously injected QDs were shown to be taken up by macrophages and localize to experimental glioma in a rat model using optical detection [147].

In this study, fluticasone and ciclesonide were used as tool compounds to explore the possibility of demonstrating both efficacy and side effects in a rat model using pulmonary delivery via intratracheal (IT) instillation with nanosuspension formulations.

To evaluate the utility of gene therapy for uterine fibroids in the Eker rat model using an adenovirus-mediated delivery of a dominant-negative estrogen receptor gene (Ad-DNER).

In this study a tissue engineering approach was compared with a macroencapsulation approach to reverse type 1 diabetes in a rat model, using mouse pancreatic progenitor cell (PPC -derived islet-like clusters and mouse islets.