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In contrast to the rat models, the mouse PGIA model is a chronic and progressive model of RA [27].
In HG/HI and ZDF fa/fa rat models, the geometric mean of respective controls (ZDF fa/+ lean or NaCl-infused rats) was used to sort βhigh-cells and βlow-cells.
Two recently developed rat models, the polyposis in the rat colon (Pirc) and Kyoto Apc Delta (KAD) strains, each carry mutations in the intestinal-cancer-associated adenomatous polyposis coli (Apc) gene.
In rat models, the inhibition of p38 MAPK by treatment with a specific p38 MAPK inhibitor resulted in reduced CAN/IFTA with preserved renal function and survival [ 43, 44].
In diabetic and obese rat models, the expression of β-defensin 1 (BD-1) was lower than that of slim rat controls [ 39] and only β-defensin 2 was found to be increased in diabetic rats, most likely as a result of a proinflammatory response [ 40].
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By applying a monocrotaline (MCT -induced rat MCT -inducedffect of Ost on ratremodeling was investheateffect
Using the rat model, the present study demonstrates some limitations.
For the rat model, the S value for 131I was 70%and90%0% lower than that for 123I and 125I, respectively.
For the rat model, the S value was 340% and 230% higher for 131I than that for 123I and 125I, respectively.
For the rat model, the S value for 131I was 6% higher and 50% lower than that for 123I and 125I, respectively.
From the Ames test and subacute toxicity test using oral administration in a rat model, the cordycepin was proved to be a non-mutagenic and non-toxic compound.
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