Sentence examples for rat models indicating from inspiring English sources

Some ERβ-selective compounds did not show any benefits on hot flashes in rat models indicating that ERβ-selective agonists might not be effective for this classical indication for HT [43].

We have demonstrated that this marker was elevated in two preclinical models of liver fibrosis, the BDL and the CCl4 rat models, indicating that this neoepitope may have potential use in assessing diseases with high turnover of the ECM.

This histomorphometric changes in their BB.4S rat models indicated that PEEK interspinous devices like the Wallis might have time-limited effects.

The observations in our rat model indicate that the liver is irreversibly programmed to respond to a nutritionally restricted environment and that this persists into early adulthood (day 55).

Anterograde tracing in the hypertensive rat model indicates that experimental glaucoma induces an overall reduction of the retinal projections to the brain (∼60%) while the same analysis following severe degeneration of outer retinal photoreceptors reveals no effects [37].

Data from a rat model indicated that arsenic has a suppressive influence on spermatogenesis and on gonadotropin and testosterone release (Sarkar et al. 2003).

A previous study in a surfactant-depleted small animal model (saline lavage rat model) indicated that aerated, nondependent regions were those predominantly affected by mechanical ventilation without limitation of end-inspiratory pressure [ 49].

Moreover, the fact that the observed synergistic effect was shown in an immune-deficient nude rat model indicates that the pro-apoptotic combination effect of IT and CsA in vitro and in vivo is not linked to the immunosuppressive activity of CsA.

A kinetic study performed in the rat model indicated that the antibacterial effect of PXL150 was very rapid with >99.9 % reduction of bacterial survival in the wounds treated with 5 mg/ml of PXL150 30 min after the peptide administration, and the effect sustained for at least 4 h post-treatment.

Rat neuroinflammation models indicate that [11C]KTP-Me enters the brain and is retained in inflammatory lesions, accumulating in activated microglia.

Findings in rat arthritis models indicate that osteoclasts are formed soon after the onset of clinical arthritis and are continuously replenished by infiltrating macrophages during disease progression [ 26].