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Using a rat model, this study was designed to compare the pharmacokinetics and tissue adsorption of intraperitoneal vs intravenous MTA.
In a subcutaneous rat model, this template was subsequently remodeled into mineralized bone tissue, including bone-marrow cavities.
Utilizing a rat model, this study investigated whether post-weaning exposure to a prototype SSRI, fluoxetine (FLX), influenced performance on visual tasks designed to measure discrimination learning, sustained attention, inhibitory control, and reaction time.
We show that in the CIA rat model this effect is independent of treatment and therefore may represent a metabolic alteration caused solely by inflammation.
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Compared with a lower LPS concentration rat model, the rats in this study experienced a normotensive endotoxemia (0 to 180 minutes) to shock status (240 minutes).
The syndrome diagnosis is reliable in the HF rat model in this study.
We have shown for the first time that this paradigm holds up in humans as well as in an established rat model of this disease.
EA at Zusanli blocked the increase in inflammatory mediators and decrease in ICC number that occurred after partial bowel obstruction in our rat model of this condition.
We compared effects of low-dose versus high-dose aspirin coadministered with ticagrelor on the reactivity of VSMCs in a rat model in this study.
Thus, the expression levels of these biomarkers vary through the life-cycle of the rat model and this may have implications for their appropriate use.
We have established a rat model resembling this situation, which develops a milder form of right ventricular hypertrophy and pulmonary artery remodelling compared to continuous chronic exposure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com