Sentence examples for rat model showing from inspiring English sources
To characterize the effects of overexpression of human full-length alpha-synuclein on hippocampal cellular and synaptic plasticity, we used a recently generated BAC alpha-synuclein transgenic rat model showing important features of PD such as widespread and progressive alpha-synuclein aggregation pathology, dopamine loss and age-dependent motor decline.
In heatstroke models, there have been conflicting results with a rat model showing improved fibrinolysis [ 49], but no change in fibrinolysis in a baboon heatstroke model [ 50].
Goto et al. (abstract 470) administered miglitol and the DPP-4 inhibitor SK-0403 in combination in a rat model, showing that after a mixed meal the combination increased GLP-1 levels to a greater extent than the DPP-4 inhibitor alone.
The protective effects of NAC on the toxic effects of particulate air pollution has been reported using in vivo model of inhalation exposure to PM in a rat model, showing that NAC treatment protected lung tissue exposed to PM from oxidative stress as well as inflammatory changes.
Chari et al. (abstract 110) normalized glucose with use of phlorizin to produce glycosuria in a streptozotocin-diabetic rat model, showing restoration of response to mediobasal hypothalamic hypoglycemia, with the glial isoform of GLUT1 reduced by 50% with hyperglycemia and returning to normal levels with treatment.
The experimental rat model showed a significant reduction in CNV in eyes treated with the 2ME2 implant.
Moreover, studies in the retrorsine-partial hepatectomy rat model showed that intraportal infusion of the fibronectin-like polymer before cell transplantation significantly accelerated liver repopulation.
In vivo testing in a femoral condyle defect rat model showed long-term MR contrast enhancement, as well as improved osteogenic capacity.
The NP applied rat model shows a shorter decrease in the withdrawal threshold (Uesugi et al. 2011; Miyoshi et al. 2011) compared to the CCI model (Vrinten and Hamers 2003) even after taking the differences in study design into consideration.
The results of polyelectrolyte coatings in a rat model showed that the Chi/Gel and Chi/HA coatings have a positive effect on mechanical implant anchorage in normal bone.
Our results in vitro and in an in vivo subcutaneous rat model show the OGP-based crosslinkers, which are small fragments of growth factors that are normally soluble, exhibit enhanced proliferative activity, accelerated degradation properties and concentration dependent bioactivity when immobilized.
