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The experimental rat model showed a significant reduction in CNV in eyes treated with the 2ME2 implant.
Moreover, studies in the retrorsine-partial hepatectomy rat model showed that intraportal infusion of the fibronectin-like polymer before cell transplantation significantly accelerated liver repopulation.
In vivo testing in a femoral condyle defect rat model showed long-term MR contrast enhancement, as well as improved osteogenic capacity.
The results of polyelectrolyte coatings in a rat model showed that the Chi/Gel and Chi/HA coatings have a positive effect on mechanical implant anchorage in normal bone.
The rat model showed an upregulation of VEGF expression by tamoxifen (Hyder et al, 1996).
The rat model showed an area under the curve in bone ≈250× higher than plasma (7 ).
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The NP applied rat model shows a shorter decrease in the withdrawal threshold (Uesugi et al. 2011; Miyoshi et al. 2011) compared to the CCI model (Vrinten and Hamers 2003) even after taking the differences in study design into consideration.
In heatstroke models, there have been conflicting results with a rat model showing improved fibrinolysis [ 49], but no change in fibrinolysis in a baboon heatstroke model [ 50].
The Pirc rat model shows a distribution of fates similar to the human: in these rats, on average, 71% of adenomas grow, whereas 25% are static and 4% regress (Irving et al., 2011; Irving, 2014).
The current study in the rat model shows that a statistically significant lack of knee extension remained despite long periods of spontaneous recovery similar to patients with fixed knee flexion contractures.
The protective effects of NAC on the toxic effects of particulate air pollution has been reported using in vivo model of inhalation exposure to PM in a rat model, showing that NAC treatment protected lung tissue exposed to PM from oxidative stress as well as inflammatory changes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com