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In vivo osseointegration studies conducted for 12 weeks on the rat model show early-stage new bone formation and the bone contact ratio (12 week) on the Zn-implanted coating is larger.
Our results in vitro and in an in vivo subcutaneous rat model show the OGP-based crosslinkers, which are small fragments of growth factors that are normally soluble, exhibit enhanced proliferative activity, accelerated degradation properties and concentration dependent bioactivity when immobilized.
Some very preliminary results with a rat model show that in principle, in vivo adsorption of superantigen is also possible.
Studies in the IR rat model show that DCs accumulate within the zones bordering infarcted tissue 7 days after myocardial infarction [ 21].
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The experimental rat model showed a significant reduction in CNV in eyes treated with the 2ME2 implant.
Moreover, studies in the retrorsine-partial hepatectomy rat model showed that intraportal infusion of the fibronectin-like polymer before cell transplantation significantly accelerated liver repopulation.
In vivo testing in a femoral condyle defect rat model showed long-term MR contrast enhancement, as well as improved osteogenic capacity.
The NP applied rat model shows a shorter decrease in the withdrawal threshold (Uesugi et al. 2011; Miyoshi et al. 2011) compared to the CCI model (Vrinten and Hamers 2003) even after taking the differences in study design into consideration.
The results of polyelectrolyte coatings in a rat model showed that the Chi/Gel and Chi/HA coatings have a positive effect on mechanical implant anchorage in normal bone.
To characterize the effects of overexpression of human full-length alpha-synuclein on hippocampal cellular and synaptic plasticity, we used a recently generated BAC alpha-synuclein transgenic rat model showing important features of PD such as widespread and progressive alpha-synuclein aggregation pathology, dopamine loss and age-dependent motor decline.
The rat model showed an upregulation of VEGF expression by tamoxifen (Hyder et al, 1996).
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