Sentence examples for rat model revealed from inspiring English sources
An experiment based on rat model revealed that oral dose of 2000 mg EGCG/kg was lethal but dose with 200 mg EGCG/kg induced no toxicity [64].
In two independent experiments, when rats received Fe-SP intraperitoneally, systemic toxicity at high concentrations (4.0 mg/Kg body weight) was not observed while treatment in an OC rat model revealed chemotherapeutic response even at low concentrations (of 0.5 1 mg/Kg body weight) including complete responses within 12 days of treatment [8].
From our ongoing work, immunohistochemistry of brain sections from 7 days after SE in an organophosphate rat model revealed an important polarizing effect of 1400 W on gliosis.
Rat model revealed decreased expression of Claudin-3 and no change of Claudin-1 and 4 [ 31, 32], while an in vitro model of esophageal-like squamous cells demonstrated a prominent role of Claudin-4 [ 33].
An experiment based on rat model revealed that oral dose delivering 2000 mg EGCG preparation/kg was lethal to rats; but dose with 200 mg EGCG/kg induced no toxicity [ 81].
In summary, the changes in cartilage and subchondral trabecular bone structure observed in the low-dose MIA rat model reveal important pathologic features of human OA and the temporal progression of the disease in the tibial subchondral bone.
A recent observation using a diabetic cardiomyopathy rat model reveals that the GLP-1 analog liraglutide improved cardiac function, which is accompanied with a decrease in activating transcription factor 4 (and4) and TNF receptor associated factor 2 (TRand) and the down-regulation of Grp78 and caspase-3.
Attempts to evaluate this series of compounds in a rat PK model revealed its instability in rat plasma.
A subsequent study performed in a rat CMV model revealed that the parent compound, artemisinin, had lower anti-CMV activity compared to artesunate [18].
Analysis of BrdU labelling in injured carotid arteries 7 days after angioplasty, a time when neointimal cell proliferation peaks in the rat carotid injury model, revealed abundant BrdU-labelled neointimal cells with sparser labelled cells present in the adventitia or media.
Conversely, In vivo rat model studies revealed that the wound healing rate and collagen deposition increased with the SF content within the nanocomposites.
