Sentence examples for rat model led from inspiring English sources

The administration of APS-loaded TES on the skin wound in a diabetic rat model led to a dose-dependent promotion in skin blood flow around wounds and an increase in endoglin expression and microvessel density in regenerated skin tissues.

Progression of dialysis-induced peritoneal fibrosis in our rat model led to impaired peritoneal function, which was indicated by reduced ultrafiltration capacity, decreased glucose reabsorption (D2/D0) and higher dialysate-to-plasma urea ratio (D/Purea).

PTH in rat models leads to improved fixation of implants in low-density bone or screw insertion transcortically.

Both carcinogenesis and chemoprevention studies using rat models lead us to better understanding of esophageal adenocarcinoma and possible preventive strategies [ 18- 23].

In conclusion, CMC/BioC/BMP-2 (0.5 mg) hybrid materials implanted in a rat tibial defect model led to greater bone formation than did CMC/BioC and CMC/BioC/BMP-2 (0.1 mg) hybrid materials.

In contrast to normotensive rats, the same stress model led to elevation of BP in SHR and SHR-mothered BHR but not in Wistar-mothered BHR after 8-week exposure.

This mutation, similar to the one present in the hyperbilirubinemic Gunn rat model (1), leads to a frameshift generating a stop codon immediately downstream (Fig. 1 B).

8 12 The rat nephrotoxic nephritis (NTN) model leads to severe Crgn in the Wistar Kyoto (WKY) rat, whereas the Lewis rat that shares the same major histocompatibility complex haplotype is NTN resistant.

In a second part, we provide an experimental proof of concept, showing that repeated intravenous injection of P. gingivalis in a rat model of AAA led to enhanced aortic dilation associated with neutrophil retention and persistence of a non-healing luminal thrombus, mimicking human physiopathology.

Similarly, in human NASH patients, serum IL-13 levels are increased and the inhibition of the IL-13 receptor in a rat model of NASH led to a reduction of fibrosis.

Consistent with these observations, our rat model of hemorrhage/resuscitation led to increased hepatic formation of both ROS and RNS, as evidenced by hepatic 4-HNE adduct formation (Fig. 4), protein nitration (Fig. 5) and increased iNOS expression (Fig 6).