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Results Here, the authors describe a new rat model lacking TP53.
Moreover, optical recordings with voltage-sensitive dyes in a rat model lacking reelin (shaking rat Kawasaki) support our finding (Higashi et al. 2005).
In an obese rat model lacking the CCK-1 receptors (Oletf), treatment with D2R antagonist raclopride, but not D1R antagonist SCH23390, showed increased potency to reduce sucrose real intake, indicating that D2R are involved in heightened increased consumption of sucrose observed in these obese rats.
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Pmch encodes for NGE, NEI, and MCH [4], and our rat model lacks all three neuropeptides [8].
We denote that heart age-specific experiments exist also in other organisms like rat model; however, the lack of sufficient biomolecular interactions hampers the comparison among organisms and therefore the rat model was excluded from analysis.
The current study in the rat model shows that a statistically significant lack of knee extension remained despite long periods of spontaneous recovery similar to patients with fixed knee flexion contractures.
Moreover, the validation of existing transgenic rat model of HD51 from this point of view is still lacking.
The cholesteryl-ester transfer-protein (CETP) is the target of HDL-modifying drugs explaining lack of pharmacological responses in the rat model [ 10].
However, use of this rat model for mechanistic and chemopreventive studies is limited due to lack of genetically modified rat strains.
The filamentous fungus Aspergillus fumigatus lacking the catalases expressed in the mycelium exhibited delayed infection in a rat model of invasive aspergillosis (Paris et al., 2003).
To address this issue we transplanted foetal dopaminergic neurons from mice lacking the dopamine transporter (DATKO) or from wild-type mice, into a rat model of Parkinson's disease and l-dopa-induced dyskinesias.
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