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The present study was designed to determine the ability of melatonin to influence MMP-9 activity and BBB disruption, in a focal ischemia rat model induced by photothrombosis.
We sought to refine an established rat model induced by exposure to 60% O2 from birth by following hyperoxia with intermittent hypoxia (IH).
Various species have been used as animal models; the rat model induced via partial BOO is the most widely used.
The present study was conducted to develop a metabolic syndrome rat model induced by the FDW even with the consumption of normal diet.
The type 1 diabetes rat model induced by streptozotocin is associated with an increased bile acid pool size due to enhanced synthesis.
Vairaktaris et al. investigated the molecular basis of the association between oral cancer and diabetes (type I) in a rat model induced by a single intraperitoneal injection of streptozotocin dissolved in saline buffer [ 71].
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We recently reported a rat model inducing IUGR and white matter damage after prenatal hypoxia and deprivation of nutritional and maternal factors [13].
In the present study, we extended the role of NF-κB in BCP rat models induced by inoculating Walker 256 mammary carcinoma cells and demonstrated that it was robustly increased in spinal astrocytes.
Although type II diabetes represents 90% of the diabetic patients, the majority of the experimental studies are performed in type I diabetic rat models, induced by streptozotocin [ 5, 25- 27].
Gullung and colleagues [ 46] compared the regenerative effects of early PRP injection and delayed PRP injection in a rat IDD model induced by needle puncture of Sprague Dawley rats.
In the rat model, PIM induced upon bile-duct ligation were shown to be responsible for endotoxin-induced mortality38.
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