Sentence examples for rat model experiments from inspiring English sources

In the rat model, experiments have shown higher amounts of type I collagen levels and lower amounts of type III collagen in capsule cells of immobilized legs compared to sham-operated legs, suggesting that the contractures were caused by fibrosis [ 15].

Fifty-four female Sprague Dawley rats (200 ± 20 g) were obtained from Medical Experimental Animal Center of Guangzhou University of Chinese Medicine for the OAB rat model experiment.

BAL was the most effective of all the compounds studied and it did not mobilize Cd to the kidney, when most of the intracellular Cd was bound to MT. Furthermore, a delayed treatment with BAL or DTPA (diethylenetriamine pentaacetic acid) after synthesis of MT resulted in an increase in fecal or urinary excretion of Cd in rat model experiment.

The most likely networks are constructed by the knowledge database, taken all available data into account of human, mouse, rat and in vitro model experiments.

In experiments with a rat model of renal IRI, Kelly [7] demonstrated an increase of circulating TNF-α by 1 h post renal ischemia, a further increase at 2 h, and steady elevation of the cytokine for 24 h.

In vivo experiments in a rat model suggest that colonocytes receive RRR-γ-tocopherol from both plasma and the contents of the digestive tract [ 10].

This conclusion is in line with experiments in the rat model that show a protective effect of hormones even after initiation by a chemical carcinogen.

On the other hand, experiments in a rat model of heart failure demonstrated that MMP activity contributed to LV dilation and progression to LV dysfunction.

We have repeated the intratracheal MSC experiments in a rat model of emphysema (elastase dose: 30 Units / 100 g bodyweight) and 5 × 10 rat bone marrow-derived MSCs (data not shown).

In turn, experiments in a rat model of DSS-induced colitis showed that treatment with butyrate leads to a recovery in transepithelial resistance, which was associated with maintenance of tight junction integrity and inhibition of TNFα release [ 100].

Experiments with captopril in a canine, porcine and rat model report a reduced myocardial injury although other experiments in canine models do not show any effect [ 16, 17].