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In order to determine if hippocampal synaptic plasticity is disrupted before plaques are deposited in this TG rat line we attempted to induce LTP of excitatory glutamatergic transmission at CA3-to-CA1 synapses in the stratum radiatum of 3 and 4 month-old freely moving animals and their WT littermates.
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Using the Ins-1 rat insulinoma line, we demonstrate that activated Rap1A, but not related monomeric G proteins, promotes ribosomal protein S6 phosphorylation.
In an uptake study using A7r5 cells – a secondary rat-VSMC line – we found a 50% reduction in incorporation of [H]thymidine into A7r5 cells transduced with Ad-miR-143 or Ad-miR-145, compared to a control miRNA-carrying Ad (Fig. 4c).
We believe that this mutant rat line will be useful in studying cancer types rarely observed in mice and in carcinogenicity assays for drug development.
We guessed the kidnappers would be running the ancient southern Haqqani rat line that runs from the Spera and Kowchun valley in Pakistan through Yaya Khel.
Through a previous kidnapping by the same gang, we had guessed that the kidnappers would be running the ancient southern Haqqani rat line that runs from the Spera and Kowchun valley in Pakistan through Yaya Khel.
In combination with the Cre reporter line CAG-loxP.EGFP, we demonstrate effective temporal regulation of Cre activity by tamoxifen treatment in the newly developed rat line CaMKIIα-CreERT2.
American military officials have said there is "a rat line" of insurgents flowing north.
The present study was designed to examine the function of the μ-opioid receptor system in rat lines selectively bred for alcohol preference (AA [Alko, Alcohol] rat line) and alcohol avoidance (ANA [Alko, Non-Alcohol] rat line).
Here we utilized a promising new technique for efficient site-specific gene modification to create a novel gene knockout rat line.
But by then Mr. Barbie had served his purpose, and the Army decided to get rid of him via the "Rat Line" to South America.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com