Sentence examples for rat knockout model from inspiring English sources

In this study we use a recently generated rat knockout model [8] to investigate how chronic loss of Pmch in the rat affects motivational or incentive-related aspects of feeding behavior.

Finally, we will highlight the huge potential impact of newly generated rat knockout models of autism.

However, the existence of additional PINK1-dependent phosphorylation sites has been suggested from the analysis of rat knockout models of PINK1 and Parkin (Dave et al, 2014).

The ENU-driven target-selected mutagenesis approach has already been used successfully for generating a variety of novel rat knockout models [ 5, 6, 16] and with the improvements described here, this approach does provide realistic technological requirements for screens on a genome-wide scale.

We tested the hypothesis that p21 is downregulated in human ADPKD tissues, and then further tested generalizability of the findings in a rat non-knockout model.

To address this, we exploit two animal models that both present phenotypically-divergent responses to exogenous ligands based on differences in AHR-status: a mouse AHR knockout model and the H/W rat model of reduced sensitivity to toxic effects of TCDD.

Osteosarcoma, brain neoplasia and hemangiosarcoma are less common in wild-type SD rats, but were the most frequent tumors in our SD Tp53 knockout model.

Finally some variety set in. "That is one knockout model," the second man said.

Kanadia, R.N. et al. A muscleblind knockout model for myotonic dystrophy.

Recently, we generated a Drosophila knockout model for optic atrophy.

Ime2 rises to infinity in the feedback knockout model.