Although reduced uterine perfusion pressure (RUPP) is widely used as a model of PE in rats, investigating the genetics of PE has been slow because it has been difficult to make a useful RUPP model in mice.
Although our study was a randomized controlled trial using rats of controlled genetics, large sample size, long intervention period and well-validated methodology [16], [28], [36], [48], [49], it had some limitations that require consideration.
Comparative genetics between rats and humans has also been used to identify breast cancer risk alleles [ 9].
We use a systems genetics approach in rat macrophages to unravel their genetic determinants of multinucleation and investigate their role in both bone homeostasis and inflammatory disease.
This resource is valuable for a broad range of researchers that use rats in biomedical and complex genetics research and may facilitate further research on rat functional genomics and interspecies comparison.
He anticipated that there was still a lot to be done in the field of molecular genetics in the rat model, and "In a relatively short time, I could build up a good position in that field".
Yeast genetics, earthquake prediction, rat behavior, fruit fly behavior, strength of material, educational value of certain curricula and evaluation methods, land subsidence, malaria prevalence, and the effects of monetary policy were among the chosen topics.
Outbred rats may more naturally reflect the varied genetics of the human population, but when small groups of outbred rats are analyzed, individual variation may be large.
Rabbits have more similarities with human beings in terms of physiology, anatomy and genetics than mice and rats [ 3].
