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Still, the rat experiments have a symbolic power that far outstrips their usefulness.
Rat experiments have demonstrated hyperaesthesia of the bladder in a colitis-associated colon-hyperalgesia model 18 and colon hyperalgesia in a cyclophosphamide-induced cystitis model 19.
As mentioned above, rat experiments have also shown that hyperesthesia of the bladder can be found in a colitis-associated colon-hyperalgesia model and that colon hyperalgesia can be found in a cyclophosphamide-induced cystitis model 8, 19, and the possibility of a neural cross-talk between the bladder and large intestine has been suggested 20, 21.
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Moreover, combined PTX-Vit.E in rat experiment had beneficial effects on radiation-induced myocardial fibrosis and left ventricular function [ 43].
In the rat model, experiments have shown higher amounts of type I collagen levels and lower amounts of type III collagen in capsule cells of immobilized legs compared to sham-operated legs, suggesting that the contractures were caused by fibrosis [ 15].
Other, less used models include zebrafish, rat, and rabbit, where primarily transplantation experiments have been performed.
This is convenient because some phenotyping experiments have many different rat strains as subjects, with all the supporting information being identical.
The healing potential of mesenchymal and adipose-derived stem cells has recently been tested with rabbit and rat models and results of such experiments have provided more consistent results than PRP-based studies.
A variety of other experiments have shown that rats can rapidly learn to use the outcome of one trial to predict the outcome of the next, and hence keep track of regular sequential dependencies in the availability of food or other rewards.
Experiments have shown that rats reactivate temporally sequenced events during sleep, suggesting they are consolidating memory.
Experiments have shown that rats can perform remarkable feats of tactile discrimination in comparison tasks involving small differences in object distance, direction, or surface texture.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com