Sentence examples for rat embryonic stem from inspiring English sources
Rat embryonic stem cells (ESCs) offer the potential for sophisticated genome engineering in this valuable biomedical model species.
For reasons scientists don't fully understand, rat embryonic stem cells have been hard to isolate (this was first achieved late last year), and scientists haven't been able to use them to make genetic changes that get fully incorporated into a new rat.
Thus, the rat embryonic stem (rES) cell is an important resource for the study of disease models.
Rat embryonic stem cells recently obtained expressed SSEA-4, SSEA-3 and SSEA-1 on top of Oct4 or Nanog [55].
Rat embryonic stem (ES) cells are not widely available for gene targeting approaches, and only recently has an ES cell-free method for making knock-out rats been reported [40].
Although the rat is extensively used as a laboratory model, the inability to utilize germ line-competent rat embryonic stem (ES) cells has been a major drawback for studies that aim to elucidate gene functions.
McKay's group published a highly regarded paper in Science last summer showing how rat embryonic-stem cells could be used to treat a version of multiple sclerosis in rats, but he doesn't dare extend the research to test the method's effectiveness in humans.
In rat embryonic neural stem cells and prenatally exposed adult rats, methylmercury reduced neural cell proliferation and was associated with global DNA hypomethylation [ 75].
In this paper, we show that rat embryonic neural stem cells (NSCs) exposed to the synthetic glucocorticoid dexamethasone (Dex) undergo heritable alterations, possibly through epigenetic mechanisms.
Scientists in Germany recently reported that rats given embryonic stem cells made from another rat could then accept transplanted hearts from the same donor, though not from different rats.
For example, in rat embryonic cortical neural stem cell cultures, LPA promotes proliferation and the formation of Map2 and choline acetyltransferase (ChAT -positive neurons and enhanChAT -positiveteneuronsCui and Qiao, 2006).
