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The minimal overlap in responses to TCDD between mouse and rat described here recapitulates and extends previous work [ 27].
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The experimental model of uremia in anephric rats described here may also be appropriate for evaluation of new biocompatible dialysis solution.
Compared to data[ 34] from non- operated rats fasted for 48 hours under otherwise identical conditions, the total amino acid release is increased by 30% in the sham- operated rats described here.
It should be noted that the rat organ culture described here, despite several similarities with the human pathological state, lacks true mechanical loading, although medium osmolarity is raised to mimic loading conditions and to counteract swelling.
The rat small RNA inventory described here will also be important for understanding human disease, since many rat models were selected to reflect clinical symptoms [ 33].
In comparison with equine cartilage, rat cartilage is much thinner and contains a growth plate, making the rat SIL model as described here essentially a model of the behaviour of the cartilage/bone subunit, rather than a simple cartilage model as in the horse.
The work described here used rat hippocampal slices to investigate the factors that initiate SPWs and govern their frequency.
The wild rat-based shotgun sequencing method described here provides an efficient approach to generate such a dense map of genetic variation.
Note that the specificity of our rat and rabbit anti-Atg8a antisera described here has recently been shown elsewhere as well., Bisected third instar larvae were inverted and fixed with 3.7% paraformaldehyde in PBS overnight at 4 °C.
There are different clinical outcomes between the treatment of traumatic vasogenic brain edema and cytotoxic edema of the same drug, if the evolution of ADC value changes of brainstem over time occurs in human DAI with acute alcoholism patients similar to that described here in our rat model; the finding of development of brain edema is of great importance on effective therapeutic strategies.
Female Wistar rats were used for the experiments described here.
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Justyna Jupowicz-Kozak
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